Decreased survival in necrotizing enterocolitis is significantly associated with neonatal and maternal blood group: the AB isoagglutinin hypothesis

Neonatal Necrotizing Enterocolitis

Neonatal Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) is a gastrointestinal disease that mostly affects premature infants. It involves infection and inflammation that causes destruction of the bowel. Although it affects only 1 in 2,000 to 4,000 births, or between 1 and 5% of neonatal intensive care unit admissions, NEC is the most common and serious gastrointestinal disorder among hospitalized preterm infants. We pr...

Neonatal necrotizing enterocolitis associated with penicillin-resistant, toxigenic Clostridium butyricum.

The cause of neonatal necrotizing enterocolitis (NEC) is unknown. An association between NEC and clostridial infection has been reported from several centers, but the organisms have not been extensively characterized. Clostridium butyricum was isolated from the peritoneal fluid and cerebrospinal fluid of a neonate with NEC. The organism was resistant to the penicillins, but sensitive to vancomy...

Intestinal vascular endothelial growth factor is decreased in necrotizing enterocolitis.

BACKGROUND Decreased intestinal perfusion may contribute to the development of necrotizing enterocolitis (NEC). Vascular endothelial growth factor (VEGF) is an angiogenic protein necessary for the development and maintenance of capillary networks. Whether VEGF is dysregulated in NEC remains unknown. OBJECTIVES The objective of this study was to determine whether intestinal VEGF expression is ...

Neonatal Necrotizing Enterocolitis: Radiological Manifistations

Objective: The aim of this study is to determine the characteristics radiological manifestations and risk factors in neonates with necrotizing enterocolitis (NEC). Methods: A prospective study over on year starting from January 2008, conducted on 55 neonates with suspected NEC admitted at Children Hospital, Cairo University. Serial X-ray for all neonates were done and assessed Results: 31 (56.4...